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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAD
All Species:
9.7
Human Site:
Y271
Identified Species:
23.7
UniProt:
P27708
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27708
NP_004332.2
2225
242984
Y271
A
K
T
Y
K
M
R
Y
G
N
R
G
H
N
Q
Chimpanzee
Pan troglodytes
XP_001155357
2225
242993
Y271
A
K
T
Y
K
M
R
Y
G
N
R
G
H
N
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540124
2288
250188
Y317
A
K
T
Y
K
M
R
Y
G
N
R
G
H
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C196
1500
164599
Rat
Rattus norvegicus
P07756
1500
164561
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001009884
2230
247184
N273
T
Y
K
M
K
Y
G
N
R
G
H
N
Q
P
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05990
2224
246654
C281
L
L
A
K
A
I
G
C
S
T
Y
K
M
K
Y
Honey Bee
Apis mellifera
XP_393888
2241
249499
M283
A
G
C
V
T
Y
K
M
N
Y
G
N
R
G
H
Nematode Worm
Caenorhab. elegans
NP_495838
2198
242563
K268
L
S
R
A
I
G
A
K
T
Y
K
L
K
Y
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07259
2214
245107
T316
A
R
A
A
G
A
S
T
L
K
L
K
F
G
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
94.8
N.A.
36.2
36.3
N.A.
N.A.
N.A.
N.A.
76.8
N.A.
64.5
63.6
57.8
N.A.
Protein Similarity:
100
100
N.A.
95.8
N.A.
48.5
48.6
N.A.
N.A.
N.A.
N.A.
86
N.A.
77.4
78
73.3
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
6.6
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
51.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
69
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
20
20
10
10
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
10
0
0
10
10
20
0
30
10
10
30
0
20
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
30
0
10
% H
% Ile:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
30
10
10
40
0
10
10
0
10
10
20
10
10
0
% K
% Leu:
20
10
0
0
0
0
0
0
10
0
10
10
0
0
0
% L
% Met:
0
0
0
10
0
30
0
10
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
30
0
20
0
30
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
30
% Q
% Arg:
0
10
10
0
0
0
30
0
10
0
30
0
10
0
0
% R
% Ser:
0
10
0
0
0
0
10
0
10
0
0
0
0
0
0
% S
% Thr:
10
0
30
0
10
0
0
10
10
10
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
30
0
20
0
30
0
20
10
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _